Our suite of programs has been extensively studied through scientific research including randomized, controlled trials. As a result, our scientific partners have published their research in leading academic journals.

A sample of some of these publications is listed below.



Saving clinicians' time by delegating routine aspects of therapy to a computer: a randomized controlled trial in phobia/panic disorder

Marks IM, Kenwright M, McDonough M, Whittaker M, Mataix-Cols D.




The Feasibility and Effectiveness of Computer-Guided CBT (FearFighter) in a Rural Area

Linda Hayward, Alastair D. MacGregor, David F. Peck and Peter Wilkes




Computer-aided vs. tutor-delivered teaching of exposure therapy for phobia/panic: Randomized controlled trial with pre-registration nursing students

L. Gega, I.J. Norman, I.M. Marks




Computer-aided CBT self-help for anxiety and depressive disorders: Experience of a London clinic and future directions

Lina Gega, Isaac Marks, David Mataix-Cols




Internet-Guided Self-Help with or without Exposure Therapy for Phobic and Panic Disorders

Andreas J. Schneider, David Mataix-Cols, Isaac M. Marks, Martin Bachofen




Logging on for Better Sleep: RCT of the Effectiveness of Online Treatment for Insomnia

Norah Vincent, PhD and Samantha Lewycky, MA




Logging on for nodding off: Empowering individuals to improve their sleep

Norah Vincent




Computer-based psychological treatment for comorbid depression and problematic alcohol and/or cannabis use: a randomized controlled trial of clinical efficacy

Frances J. Kay-Lambkin, Amanda L. Baker, Terry J. Lewin, Vaughan J. Carr




Computer-Aided psychotherapy for anxiety disorders: A meta-analytic review

Cuijpers, P., Marks, I.M., Straten, A. van, Cavanagh, K, Gega, L., Andersson, G.




Meta-analysis of computer-aided psychotherapy: Problems and Partial Solutions

Marks, I.M., Cuijpers, P. Cavanagh, K, Straten, A. van, Gega, L., Andersson, G.




Computer-Aided Cognitive Behaviour Therapy

Baer L, Greist J, Marks IM




Computer-Aided Self-Exposure Therapy for Phobia/Panic Disorder: A Pilot Economic Evaluation

McCrone, Paul1; Marks, Isaac; Mataix-Cols, David; Kenwright, Mark; McDonough, Michael




Attrition and adherence in the online treatment of chronic insomnia

Hebert EA, Vincent N, Lewycky S, Walsh K.




Are personality dimensions associated with sleep length in a large nationally representative sample?

Norah Vincent, Brian Cox and Ian Clara




Reading about... self-help books for phobias and panic disorder

Miquel A. Fullana, Isaac M. Marks




Mental Health Clinics in the 21st Century

Isaac Marks




Self-help for phobias and panic disorders

Miquel A. Fullana, Isaac M. Marks




Randomized controlled trial of cognitive–behavioural therapy for coexisting depression and alcohol problems: short-term outcome

Amanda L. Baker, David J. Kavanagh, Frances J. Kay-Lambkin, Sally A. Hunt, Terry J. Lewin, Vaughan J. Carr, Jennifer Connolly




An improved brief measure of cannabis misuse: The Cannabis Use Disorders Identification Test-Revised (CUDIT-R)

Simon J. Adamson, Frances J. Kay-Lambkin, Amanda L. Baker, Terry J. Lewin, Louise Thornton, Brian J. Kelly and J. Douglas Sellman




The long and the short of treatments for alcohol or cannabis misuse among people with severe mental disorders

Amanda Baker, Alyna Turner, Frances J. Kay-Lambkin and Terry J. Lewin




Stepping through treatment: Reflections on an adaptive treatment strategy among methamphetamine users with depression

Frances J. Kay-Lambkin, Amanda L. Baker, Rebecca McKetin, Nicole Lee




Information technology can pull mental health care into the 21st century

Isaac Marks




Teaching medical students exposure therapy for phobia/panic – randomized, controlled comparison of face-to-face tutorial in small groups vs. solo computer instruction

Michael McDonough, Isaac M Marks




Psychotherapy by computer: A postal survey of responders to a teletext article

Candida Graham, Locum Consultant Psychiatrist and Abigail Franses, Research Associate Mark Kenwright, Nurse Therapist and Isaac Marks, Professor of Experimental Psychotherapy




The maturing of therapy: Some brief psychotherapies help anxiety/depressive disorders but mechanisms of action are unclear

Isaac M. Marks, FRCPsych




Computer-Aided Psychological Treatments: Evolving Issues

Isaac Marks, Kate Cavanagh




Screening People With Anxiety/Depression for Suitability for Guided Self-help

Lina Gega, Mark Kenwright, David Mataix-Cols, Rachel Cameron and Isaac M. Marks